Dr. Vijaya Gowri

MBBS- Gandhi Medical College Bhopal, MP. MD Paediatrics , INHS ASWINI, Naval Command Hospital Mumbai, Maharashtra. Fellowship in Paediatric Immunology, B.J.Wadia Hospital for children, Mumbai, Maharashtra. Served in Indian Army Medical Corps (AMC) and exited SSC tenure as MAJOR. Have been a part of AMC team serving in field areas of J&K during OP-VIJAY (KARGIL) Was a practicing Paediatrician for around 18 years before embarking upon the Immunology superspeciality. Consultant Immunologist since last 8 years, first 7 years in Dept of Immunology, BJWHC and last 1 year in Coimbatore. An Immunologist is a specialist trained to diagnose these presumed rare diseases through specialised investigations and genetic tests to look for underlying cause.

• Consultant Immunologist since last 8 years with exposure to both children and adults who present with Inborn Errors of Immunity that has a genetic basis. 
• Inborn Errors of Immunity or IEI are a heterogeneous group of inherited disorders of the immune system, that are genetic in origin It involves management of patients (child or adult) as a TEAM with other speciality who present with recurrent infections with common organisms or infection with unusual organism including EBV associated lymphoproliferation.
• It also involoves management of patients with multiple auto-immunity driven by underlying genetic defect.
• Management of auto-inflammation eg early onset SLE, specially in children less than 5 years, where identification of underlying genetic defect can ppave way for definitive therapy. Recurrent malignancy or unusual age or site of a cancer can have a genetic basis. Similarly, Familial Cancer syndromes too have genetic cause.
• This is not restricted to Pediatric age group as many IEI’s have adult onset. 
• Treatment is decided based on the pathophysiology driving the disease process.  
• Immunological diseases can manifest at any age and is treatable with specialised targeted drugs.

• Contributed to 56+ publications in International journals with H-INDEX of 10, Citations-357
• Contributed Chapters as author to 4 books
• Presented Papers at National and International conferences
• Faculty in International and National Immunology / Rare disease conference, Infectious disease conference
• Was part of Phase 3 clinical trial for IVIG in patients with IEI as Co-Principal Investigator
• Part of Conference Secretariat- International & National conferences 
• Speciality Teacher for Immunology Fellowship Course (MUHS Nashik)

Few direct publications cited as below:

• 1. Human BCL10 Deficiency due to Homozygosity for a Rare Allele. February 2020
• Journal of Clinical Immunology 
• 2.    Malignancy associated Haemophagocytic histiocytosis – A single center experience – October 2020 – Pediatric Hematology Oncology Journal
• 3.    Clinical and Genetic Spectrum of a Large Cohort of Patients With Leukocyte Adhesion Deficiency Type 1 and 3: A Multicentric Study From India. December 2020 - Frontiers in Immunology
• 4.    Clinical and Genetic Profile of X-Linked Agammaglobulinemia: A Multicenter Experience From India - January 2021 - Frontiers in Immunology
• 5.    Clinical, Immunological, and Molecular Features of Severe Combined Immune Deficiency: A Multi-Institutional Experience From India – February 2021 - Frontiers in Immunology
• 6.    Clinical, Immunological, and Molecular Profile of Chronic Granulomatous Disease: A Multi-Centric Study of 236 Patients From India. February 2021 - Frontiers in Immunology
• 7.    Clinical and Molecular Findings in Mendelian Susceptibility to Mycobacterial Diseases: Experience From India. February 2021 Frontiers in Immunology 
• 8.    Clinical Profile of Hyper-IgE Syndrome in India. February 2021 Frontiers in Immunology
• 9.    The Spectrum of Clinical, Immunological, and Molecular Findings in Familial Hemophagocytic Lymphohistiocytosis: Experience From India. March 2021 Frontiers in Immunology
• 10.    Spectrum of Systemic Auto-Inflammatory Diseases in India: A Multi-Centric Experience. March 2021 Frontiers in Immunology
• 11.    Wiskott Aldrich Syndrome: A multi-institutional experience from India. April 2021 Frontiers in Immunology
• 12.    Innate Immune Defects. August 2021 Indian Journal of Practical Pediatrics. 
• 13.    DADA2 presenting as non-immune hemolytic anemia with recurrent macrophage activation syndrome - November 2021 - Pediatric Blood and Cancer
• 14.    Vanishing Lymphocytes in a Case of Vanishing Bone Disease. 
• January 2022 - Journal of Clinical Immunology
• 15.    STAT 3 GOF with Polycythemia: a Twist to the Tale-First Case Report from India
• February 2022 - Journal of Clinical Immunology
• 16.    XMEN saved by magnesium. March 2022 - Scandinavian Journal of Immunology
• 17.    Leukocyte adhesion defect: Clinical correlation with integrin expression and genetics
• July 2022 - WJWCH Journal
• 18.    SPENCD Presenting with Evans Phenotype and Clinical Response to JAK1/2 Inhibitors—a Report of 2 Cases – November 2022 - Journal of Clinical Immunology.
• 19.    Clinical features, laboratory and molecular findings of children with leukocyte adhesion deficiency type-III from a single center in India – November 2022 – Pediatric Hematology Oncology Journal
• 20.    Utility of HLA‐DR in screening panel for inborn errors of immunity - November 2022- Scandinavian Journal of Immunology.
• 21.    Clinical, immunological and molecular findings of patients with DOCK-8 deficiency from India. - 
• April 2023 - Scandinavian Journal of Immunology
• 22.    Lymphoproliferation- a clue towards an underlying monogenic disorder of immune dysregulation- a retrospective analysis from a single center in India - May 2023 - Clinical Immunology
• 23.    Monogenic inborn errors of immunity in autoimmune disorders - May 2023 - Clinical Immunology
• 24.    Caspase-8 deficiency-a rare cause of immune dysregulation – First case report from India - May 2023 - Wadia Journal of Women and Child health. 
• 25.    Monogenic inborn errors of immunity in autoimmune disorders - May 2023 - Immunologic Research
• 26.    Cleavage-resistant RIPK1-induced autoinflammatory syndrome-A report of three generations with periodic fever and clinical response to colchicine - July 2023 - International Journal of Rheumatic Disease 
• 27.    Normative data for paediatric lymphocyte subsets: A pilot study from western India - September 2023 - The Indian Journal of Medical Research 
• 28.    Pediatric Pancytopenia and Monosomy 7: A Case Report of SAMD9L-Associated Disease
• January 2024 – Journal of Clinical Immunology 
• 29.    Genetic susceptibility to Tuberculosis in an infant with BCG-osis - February 2024 - Wadia Journal of Women and Child Health
• 30.    Understanding the relevance of immunological markers in severe multisystem inflammatory syndrome in children through machine learning - July 2024 - Journal of Laboratory Physicians
• 31.    Interferon Alpha Therapy in MSMD - August 2024 - Journal of Clinical Immunology
• 32.    Mutational Landscape of Patients with Wiskott Aldrich Syndrome: Update from India – December 2024 - Journal of Clinical Immunology
• 33.    Baricitinib as a Steroid Sparing Agent to Curb the Immune Dysregulation Associated With Heterozygous STAT3 Mutations Causing Gain‐Of‐Function: A Case Report - May 2025 - International Journal of Rheumatic Diseases
• 34.    Common Variable Immunodeficiency Disorder: A Decade of Insights from a Cohort of 150 Patients in India and the Use of Machine Learning Algorithms to Predict Severity - May 2025 – Journal of Clinical Immunology 

Chapter publications – 

• 1.    Infections in Primary Immunodeficiency (PID) Chapter in the Textbook: Evidence Based Practices in Management of Infectious diseases in Pediatrics. 
• 2.    Acquired Immuno Deficiency - Evidence Based Practices in Management of Infectious diseases in Pediatrics. 
• 3.    ''Enteroviral Meningitis: Do We Need to Probe Further?'' – 51 fascinating Fevers Evangel publications  
• 4. Long standing Lymphadenopathy- Think out of the box
• From case records of Department of Inborn Errors of Immunity (IEI), B.J. Wadia hospital for children, Parel, Mumbai- 51 fascinating Fevers Evangel publications  

• Indian Academy of Pediatrics (IAP)
• Indian Society of Primary Immune Defeciency (ISPID)
• Asian Society of Primary Immune Defeciency (ASPID)
• European Society of Immune Defeciency (ESID)