Dr. P.L. Sreenivasan

Dr. Sreenivasan’s clinical approach emphasizes evidence-based, patient-centered endocrine care with a strong focus on metabolic health, genetic endocrinology, pediatric endocrine disorders, and multidisciplinary collaboration.

Comprehensive Endocrine and Diabetes Care

• Advanced management of Type 1 and Type 2 Diabetes Mellitus
• Thyroid disorders including thyroid nodules and thyroid cancers
• Adrenal disorders and metabolic bone diseases
• Reproductive endocrinology and infertility-related endocrine disorders
• Polycystic Ovary Syndrome (PCOS)
• Pediatric endocrinology and growth disorders
• Obesity and metabolic syndrome
• Pituitary disorders and complex endocrine conditions

• Gold medal pathology 2nd MBBS
• Certificate of Merit pharmacology 2nd MBBS
• Winner Clinico pathological case discussion - Empower international medical congress 2016 Stanely medical college, AXON 2015 and 2016 ,PSGIMSR
• Best outgoing student - Institute of internal medicine, Madras medical college during post graduation
• Best poster presentation T- Endocon 2024 and 2025 Trivandrum medical college - National endocrinology conference
• Dr.V.Mohan and TN MGR university gold medal in DM Endocrinology
• Dr. Kannan endowment gold medal for best outgoing postgraduate DM Endocrinology
• National Finalist ESI - TYSA torrent young scholar award

Original Research & Clinical Studies

• 1)S Sridhar, P Sreenivasan, Refractory headache, deafness and multiple lytic lesions—Paget’s disease, QJM: An International Journal of Medicine, Volume 117, Issue 9, September 2024, Pages 663–664, https://doi.org/10.1093/qjmed/hcae088
• 2)Sumathy S, Palanivel S, Nagaraju K, Harisankar CNB, Ashok raja J, Senthilkumar J, Sreenivasan P, Sridhar S. The Role of Neck Ultrasonography and Nuclear Imaging in the Diagnosis of Congenital Hypothyroidism. Indian J Endocrinol Metab. 2024 Nov Dec;28(6):611-616. doi: 10.4103/ijem.ijem_7_24. Epub 2024 Dec 30.
• 3)Sinju S, Sridhar S, Sreenivasan P, Paramasivam S, Varadarajan G, Mahalakshmi NK, Gnanasekharan T, Natarajan V. A Randomized Controlled Trial Comparing Testosterone Enanthate and Testosterone Undecanoate as a Gender Affirming Hormonal Therapy in Trans Males. Clin Endocrinol (Oxf). 2025 Feb 26. doi: 10.1111/cen.15223
• 4)Sridhar S, Sankar S, Subramanian A, Murugan G, Thangavel G, Amutha G, Sreenivasan P, Andiappan R. Gender-affirming medical and surgical treatment experience in a multi-specialty transgender clinic from Tamil Nadu. J Family Med PrimCare. 2025 Oct;14(10):4231-4236. doi: 10.4103/jfmpc.jfmpc_336_25.
• 5) Sreekumar S, Sridhar S, Sreenivasan P, Palanivel S, Chidambara Manivasagam VS,Shanmugam D. Inherited Lipodystrophy Associated with POLD1 and CAVIN1 Mutations: Two Cases From the Indian Subcontinent. Cureus. 2025 Jun 23;17(6):e86622.doi: 10.7759/cureus.86622
• 6) Subbiah S, Raja R, Shanmugam D, Palaniappan S, Shanmugam S, Aravind Kumar M.Validation of Peak Growth Hormone Levels After Clonidine and Glucagon Stimulation Tests in Children With Severe Short Stature. Cureus. 2025 Dec 25;17(12):e100084. doi:10.7759/cureus.100084
• 7) Sridhar S, Muthu AK, Palaniappan S, Nandini K, Chandrasekaran A, Kalavathy R. Rare phenotypic spectrum of 17β-hydroxysteroid dehydrogenase 3 deficiency: case series from infancy to adolescence. J Pediatr Endocrinol Metab. 2026 Jan 26. doi: 10.1515/jpem-2025-0549
• 8) Dhivya S, Sridhar S, Kathirvel M, Sreenivasan P, Kuppusamy N, Chellapillai R, SenthilKumar J. Clinical and molecular genetic analysis of children with severe short stature due to isolated growth hormone deficiency: insights from a South Indian cohort and predictors of growth response. Pituitary. 2025 Dec 22;29(1):23. doi: 10.1007/s11102-025-01625-x
• 9) Sridhar S, Sinju S, Sankarraj A, Rahila C, Sreenivasan P, Varadarajan G. The effectsof testosterone gender-affirming hormonal therapy on body composition and psychosocial well-being in transmen.Indian J Endocrinol Metab. Submitted: 24 Sep 2025; Accepted: 21 Nov 2025
• 10) Subbiah S, Palaniappan S, Shanmugam D, Kathirvel M, Sengottaiyan P, Jeyachandran S, et al. A comprehensive clinical and molecular genetic analysis of syndromic short stature children and response to recombinant growth hormone therapy.Pediatr Endocrinol Diabetes Metab. 2025.Manuscript No: PEDM-00406-2025-03. Submitted: 15 Aug 2025; Accepted: 1 Dec 2025
• 11)Shanmugham D, Subbiah S, Kathirvel M, Palaniappan S, Kumar MA. MC4R-related monogenic obesity in children: insights from two cases. Ann Pediatr Endocrinol Metab. Accepted for publication: 04 Nov 2025
• 12) Sreenivasan P, Palanivel S, Gnanamuthu J, Sridhar S. A rare thyroid malignancy with diverse management options: Primary thyroid lymphoma. IJEM Case Rep 2025; 3:108-12
• 13) Sreenivasan P, Sridhar S, Alagusundaram J, Chellapillai R. Efficacy comparison of tamoxifen versus letrozole in pubertal gynecomastia: a randomized controlled trial. Clinical Endocrinology. Submitted: 18 Dec 2025. Under review.
• 14)Sridhar S, Sreenivasan P, Thasarathan S, Palanivel S, Dutta P. A novel LHX3 variant causing combined pituitary hormonal deficiency: reports of Indian kindred. ASEAN J Assoc Endocr Soc. Submitted: 05 Jul 2025. Under review.
• 15) Sridhar S, Sreenivasan P, Synthiah A, Manickam N, Alagavenkatesan VN. Severe gestational hypertriglyceridemia due to APO C-II mutation: management challenges during pregnancy and review of evidence-based practices – a case report. J Assoc Physicians India. Manuscript submitted: 15 Aug 2025; Revised: 23 Jun 2025.Under review

• Association of Physicians of India (API)
• Indian Medical Association (IMA)
• Endocrine Society of Tamil Nadu & Puducherry (ESTN)
• Endocrine Society of India (ESI)