Dr. P.L. Sreenivasan

Dr. PL Sreenivasan completed his MBBS from Thanjavur Medical College. He secured AIR 213 in NEET-PG 2019, following which he pursued MD in Internal Medicine at the prestigious Institute of Internal Medicine, Madras Medical College, Chennai.

He has consistently excelled in national-level postgraduate entrance examinations, securing AIR 46 in PGI (November 2018) and AIR 120 in JIPMER (November 2018). Subsequently, he secured All India Rank 25 in NEET-SS 2022 and pursued DM in Endocrinology at the prestigious Government Rajaji Hospital, Madurai Medical College, under the mentorship and guidance of Professor Dr.S. Sridhar. 

He has extensive clinical experience in managing a wide spectrum of endocrine disorders, having cared for a large number of patients with diabetes and complex endocrine conditions, including paediatric diabetes and childhood endocrine disorders. 

His areas of clinical interest include diabetes, thyroid disorders, obesity, paediatric endocrinology, endocrine genetics and metabolic bone disorders. 

He has actively contributed to academic endocrinology through research presentations at national conferences, award-winning poster and oral presentations, academic quiz achievements and peer-reviewed scientific publications. His academic interests include clinical endocrinology, paediatric endocrinology and endocrine genetics.

Comprehensive Endocrine and Diabetes Care

• Advanced management of Type 1 and Type 2 Diabetes Mellitus
• Thyroid disorders including thyroid nodules and thyroid cancers
• Adrenal disorders and metabolic bone diseases
• Reproductive endocrinology and infertility-related endocrine disorders
• Polycystic Ovary Syndrome (PCOS)
• Pediatric endocrinology and growth disorders
• Obesity and metabolic syndrome
• Pituitary disorders and complex endocrine conditions
• Transgender care

• Gold medal pathology 2nd MBBS
• Certificate of Merit pharmacology 2nd MBBS
• Best outgoing student - Institute of Internal Medicine, Madras medical college during post graduation
• Dr.V.Mohan and TN MGR university gold medal in DM Endocrinology
• Dr. Kannan endowment gold medal for best outgoing postgraduate DM Endocrinology
• National Finalist ESI - TYSA torrent young scholar award
• Winner Clinicopathological case discussion Axon 2015 Undergraduate Conference PSGIMSR Coimbatore 
• Winner Clinicopathological case discussion Axon 2016 Undergraduate Conference PSGIMSR Coimbatore 
• Winner Clinicopathological case discussion - Empower International Medical Congress, Stanley Medical College, 2016 
• Winner - Case presentation - CHARM 2015, Chengalpattu Medical College 
• Winner Med amaze -Medical Treasure Hunt - Empower International Medical Congress, Stanley Medical College, 2015
• First Prize - Poster Presentation - Clinical Spectrum of Skeletal Dysplasia with Genotype Correlation, T-ENDOCON 2024, Trivandrum Medical College, Kerala 
• First Prize - DM Quiz competition, T-ENDOCON 2024, Trivandrum Medical College, Kerala 
• First Prize - Poster Presentation - Neck ultrasonography and nuclear imaging profile of congenital hypothyroidism - a single centre experience in South India, PEDTRENDO 2024, Madurai, Tamil Nadu  
• Third prize - Poster Presentation Precision Medicine in Neonatal Diabetes - A short Case series, PEDTRENDO, Salem, Tamil Nadu 
• Third Prize - Oral Presentation - A Randomized Comparative study on Tamoxifen and Letrozole in treatment of Pubertal Gynecomastia 
• Third prize -Poster Presentation - The MC4R Enigma and Monogenic obesity- A Tale of two cases, T-ENDOCON, Trivandrum, Kerala 
• Third Prize - DM Quiz competition, T-ENDOCON, Trivandrum, Kerala

Original Research & Clinical Studies

• S Sridhar, P Sreenivasan, Refractory headache, deafness and multiple lytic lesions—Paget’s disease, QJM: An International Journal of Medicine, Volume 117, Issue 9, September 2024, Pages 663–664, https://doi.org/10.1093/qjmed/hcae088
• Sumathy S, Palanivel S, Nagaraju K, Harisankar CNB, Ashok raja J, Senthilkumar J, Sreenivasan P, Sridhar S. The Role of Neck Ultrasonography and Nuclear Imaging in the Diagnosis of Congenital Hypothyroidism. Indian J Endocrinol Metab. 2024 Nov Dec;28(6):611-616. doi: 10.4103/ijem.ijem_7_24. Epub 2024 Dec 30.
• Sinju S, Sridhar S, Sreenivasan P, Paramasivam S, Varadarajan G, Mahalakshmi NK, Gnanasekharan T, Natarajan V. A Randomized Controlled Trial Comparing Testosterone Enanthate and Testosterone Undecanoate as a Gender Affirming Hormonal Therapy in Trans Males. Clin Endocrinol (Oxf). 2025 Feb 26. doi: 10.1111/cen.15223
• Sridhar S, Sankar S, Subramanian A, Murugan G, Thangavel G, Amutha G, Sreenivasan P, Andiappan R. Gender-affirming medical and surgical treatment experience in a multi-specialty transgender clinic from Tamil Nadu. J Family Med PrimCare. 2025 Oct;14(10):4231-4236. doi: 10.4103/jfmpc.jfmpc_336_25.
• Sreekumar S, Sridhar S, Sreenivasan P, Palanivel S, Chidambara Manivasagam VS,Shanmugam D. Inherited Lipodystrophy Associated with POLD1 and CAVIN1 Mutations: Two Cases From the Indian Subcontinent. Cureus. 2025 Jun 23;17(6):e86622.doi: 10.7759/cureus.86622
•  Subbiah S, Raja R, Shanmugam D, Palaniappan S, Shanmugam S, Aravind Kumar M.Validation of Peak Growth Hormone Levels After Clonidine and Glucagon Stimulation Tests in Children With Severe Short Stature. Cureus. 2025 Dec 25;17(12):e100084. doi:10.7759/cureus.100084
• Sridhar S, Muthu AK, Palaniappan S, Nandini K, Chandrasekaran A, Kalavathy R. Rare phenotypic spectrum of 17β-hydroxysteroid dehydrogenase 3 deficiency: case series from infancy to adolescence. J Pediatr Endocrinol Metab. 2026 Jan 26. doi: 10.1515/jpem-2025-0549
•  Dhivya S, Sridhar S, Kathirvel M, Sreenivasan P, Kuppusamy N, Chellapillai R, SenthilKumar J. Clinical and molecular genetic analysis of children with severe short stature due to isolated growth hormone deficiency: insights from a South Indian cohort and predictors of growth response. Pituitary. 2025 Dec 22;29(1):23. doi: 10.1007/s11102-025-01625-x
•  Sridhar, Subbiah & Sinju, Sankar & Sankarraj, Anuradha & Rahila, Chellapillai & Palaniappan, Sreenivasan & Varadarajan, Geethaanjali. (2026). The Effects of Testosterone Gender-Affirming Hormonal Therapy on Body Composition and Psychosocial Well-being in Transmen. Indian Journal of Endocrinology and Metabolism. 30. 449-455. 10.4103/ijem.ijem_887_25. 
•  Sridhar S, Palaniappan S, Shanmugam D, Manjini K, Sengottaiyan P, Jeyachandran S. A  comprehensive clinical and molecular genetic analysis of syndromic short stature children and response to recombinant growth hormone therapy. Pediatr Endocrinol Diabetes Metab. 2026 Mar;32(1):13–25. doi: 10.5114/pedm.2026
• Shanmugam D, Sridhar S, Kuppusamy N, Manjini K, Sreenivasan P, Kumar MA. Author Correction: MC4R-related monogenic obesity in children: insights from 2 cases. Ann Pediatr Endocrinol Metab. 2026 Jun;31(3):206. doi: 10.6065/apem.2026.err01. Epub 2026 Jun 30. Erratum for: Ann Pediatr Endocrinol Metab. 2026 Apr;31(2):138-145. doi: 10.6065/apem.2550160.080
•  Sreenivasan P, Palanivel S, Gnanamuthu J, Sridhar S. A rare thyroid malignancy with diverse management options: Primary thyroid lymphoma. IJEM Case Rep 2025; 3:108-12
•  Sreenivasan P, Sridhar S, Alagusundaram J, Chellapillai R. A Prospective Comparative Study of Tamoxifen Versus Letrozole in Pubertal Gynecomastia . Accepted . IJEM 21 October 2026
• Palaniappan S, Sridhar S, Thasarathan S, Shanmugam D, Dutta P. A Novel LHX3 Variant Associated With Combined Pituitary Hormone Deficiency in an Indian Kindred. Cureus. 2026 Jun 29;18(6):e111778. doi: 10.7759/cureus.111778
• Sridhar S, Sreenivasan P, Synthiah A, Manickam N, Alagavenkatesan VN. Severe gestational hypertriglyceridemia due to APO C-II mutation: management challenges during pregnancy and review of evidence-based practices – a case report. J Assoc Physicians India. Manuscript submitted: 15 Aug 2025; Revised: 23 Jun 2025.Under review

• Genetics and Precision Medicine in Neonatal Diabetes – A Short Case Series, PED-TRENDO 2023.
• Childhood-onset Recurrent Fractures with Familial Clustering: Osteogenesis Imperfecta, PED-TRENDO 2023.
• Novel LHX3 Mutation in Siblings with Combined Pituitary Hormonal Deficiency, TRENDO 2024.
• A Diverse Genetic Profile of Syndromic Short Stature and Response to rhGH Therapy, TRENDO 2024.
• Utility of Basal LH, Single Stimulated LH, and LH/FSH Ratio in Central Precocious Puberty, TRENDO 2024.
• Clinical Spectrum and Molecular Genetic Analysis of Skeletal Dysplasia in a Cohort of Severe Short Stature, T-ENDOCON 2024.
• Neck Ultrasonography and Nuclear Imaging in the Diagnosis of Congenital Hypothyroidism, T-ENDOCON 2024.
• A Rare Thyroid Malignancy: Primary Thyroid Lymphoma, ESICON 2024.
• A Unique Tale of Primary Amenorrhea with Premature Ovarian Insufficiency: A Case Report of Novel FSH Receptor Mutation, ESICON 2024.
• Randomized Comparative Study to Assess the Efficacy of Tamoxifen and Letrozole in Pubertal Gynecomastia,ESICON 2024.
• Diabetes and Nutrition Case Presentation, Vellore Endocrinology International Congress 2025
• The MC4R Enigma and Monogenic Obesity: A Tale of Two Cases, T-ENDOCON 2025.
• Navigating the Unforeseen: APOC2-Related Hypertriglyceridemia in Pregnancy and the Pivotal Role of the Insulin–Dextrose Strategy.

• Association of Physicians of India (API)
• Indian Medical Association (IMA)
• Endocrine Society of Tamil Nadu & Puducherry (ESTN)
• Indian Society for Pediatric and Adolescent Endocrinology (ISPAE)
• Endocrine Society of India (ESI)